Human Papillomavirus E6 Knockdown Restores Adenovirus Mediated-estrogen Response Element Linked p53 Gene Transfer in HeLa Cells
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منابع مشابه
HPV E6 Knockdown Restores Adenovirus Mediated-Estrogen Response Element Linked p53 Gene Transfer in HeLa Cells
p53 is inactivated and degraded by the E6 protein encoded by the integrated human papillomavirus (HPV) in the cervical cancers (Scheffner et al., 1990). The susceptibility of p53 to degradation by the E6 protein varies between the arginine and proline variants at codon 72 of p53 (Storey et al., 1998). In vivo studies demonstrate that the arginine p53 variant is seven times more susceptible to d...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2016
ISSN: 1513-7368
DOI: 10.7314/apjcp.2015.16.18.8239